In addition, we see some increased risk of pancreatic cancer associated with the use of insulin and the use of insulin secretagogues. Cyclosporine: Sulfonylureas may increase the levels of cyclosporine. Hematologic Reactions Leukopenia, agranulocytosis, thrombocytopenia, hemolytic anemia, aplastic anemia, and pancytopenia have been reported with sulfonylureas, including AMARYL. Glimepiride overdose can cause life-threatening hypoglycemia. a basso costo glimepiride senza prescrizione medica durante la notte di consegna Do not change dose or discontinue without consulting prescriber. Since AMARYL belongs to the class of sulfonylurea agents, caution should be used in patients with G6PD deficiency and non-sulfonylurea alternative should be considered.